Glucocorticoids (GCs) are steroid hormones that respond to stress and the circadian rhythm.Pharmacological GCs are widely used to treat autoimmune and chronic inflammatory diseases despite their adverse effects on bone after long-term therapy.GCs regulate bone homeostasis in a cell-type specific manner, affecting osteoblasts, osteoclasts, and osteo
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Punch sticking is a common tablet compression manufacturing issue experienced during late-stage large-scale manufacturing.Prediction of punch sticking propensity and identification of the sticking component is important for early-stage formulation development.Application of novel predictive capabilities offers early-stage sticking propensity assess